Stannous chloride induced alteration in hormones : protective role of ginseng


Stannous chloride
hormones and rabbits


Roughly 50% of the world generation of tin is utilized for plating. Tin coatings are utilized for nourishment_ holders and nourishment- preparing hardware. Ginseng, which may be a plant having diverse species has been well examined, particularly the ginseng, and has been detailed to have antioxidant properties, improve safe work.. This work explored the defensive impacts of ginseng against stannous chloride (SnCl2) on hormones in rabbits. Results indicated that treatment with ginseng alone caused significant (P<0.05) increase in body weight (BW) and relative weight of testes compared to control animals. On the other hand, significant (P<0.05) decrease in BW and relative weight of testes in rabbits treated with SnCl2 compared with control. Treatment with SnCl2 caused significant (P<0.05) decrease activity of testosterone, T3 and T4. While, increase the levels of FSH, LH, estradiol and progesterone in plasma. ginseng caused significant (P<0.05) increase in the activity testosterone, T3 and T4. While, decrease the levels of FSH, LH, estradiol and progesterone in plasma compared to control. The presence of ginseng with SnCl2 caused significant (P<0.05) decrease in the reduction of testosterone ,T3 and T4 as compared to control and the presence of ginseng with SnCl2 caused increase in the levels of estradiol , progesterone, FSH and LH as compared to control, and this means that ginseng counteracted the toxic effects of SnCl2.



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